CRISPR News

CRISPR - A Discovery Timeline

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Episode notes

This timeline details the key discoveries leading to the development of CRISPR-Cas9 gene editing. It highlights the contributions of numerous scientists, from the initial observation of CRISPR sequences in bacteria to the experimental demonstration of their function as an adaptive immune system. The timeline traces the crucial steps in understanding the mechanism of CRISPR-Cas9, including the identification of Cas9, guide RNAs, and the PAM sequence. Finally, it culminates in the successful adaptation of CRISPR-Cas9 for genome editing in eukaryotic cells.