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E152 - Flipping the Youth Switch - Low Dose THC in Mice with Andras Bilkei-Gorzo

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Episode notes

Ponce de León never found the Fountain of Youth. Andras Bilkei-Gorzo from the University of Bonn in Germany thinks Ponce should have looked at low dose THC. Andras and his team have been giving mice low dose THC and finding some interesting results. Listen to how to get an older mouse to swim to an invisible platform faster, how THC can flip a metabolic switch called mTOR on and off at the same time, and why low dose THC might be better for older people than younger ones. 

Bidirectional Effect of Long-Term Δ9-Tetrahydrocannabinol Treatment on mTOR Activity and Metabolome

- paper

A chronic low dose of ∆9-tetrahydrocannabinol (THC)

restores cognitive function in old mice

- abstract

Andras Bilkei-Gorzo - LinkedIn

Transcripts, papers and so much more at: reefermed.ca